According to the Market Statsville Group (MSG), the Global Polybrene Market size is expected to grow at a CAGR of 6.4% from 2023 to 2033.

Polybrene is a synthetic compound used in molecular biology and cell biology research. Polybrene enhances the efficiency of viral transduction, a process by which genetic material is introduced into host cells using viral vectors, such as retroviruses or lentiviruses. It neutralizes the negatively charged cell surface and reduces the repulsive forces between the viral particles and the targeted cells. This electrostatic interaction facilitates the attachment of the viral vectors to the cell membrane, thereby increasing the gene transfer. Polybrene has wide application in experiments of exogenous genes or genetic modifications to cells, as it can significantly improve the transduction efficiency.

The rapidly growing gene therapy and advancements in genetic engineering are factors augmenting the market’s growth. The expansion of cell culture techniques in the biotechnology and pharmaceutical industries is contributing to the demand for polybrene market. Gene therapy has a wide application in the pharmaceutical and biotechnology sectors. Various key players are focusing on the development of new gene therapy products to create opportunities for market growth. The rise of regenerative medicine and stem cell research is another factor boosting the market’s growth. The rise in the prevalence of chronic diseases and surging demand for the development of therapies has upsurged the polybrene demand. Also, universities and research institutions are involved in the development of various new pipelines, significantly driving the market’s growth. The rise in funding and investments in gene therapy advancements as well as many biopharmaceutical firms offering resources to facilitate the introduction of innovative products is fostering the market growth. For instance, in January 2022, Ori Biotech invested around USD 100.0 million in Series B funding to roll out an innovative platform for the development of cell and gene therapies.

Polybrene Market Segmental Analysis, 2023-2033

Based on application, the market is divided into graduate school, laboratory, and others. The laboratory segment emerged as the largest market share in 2023. Laboratories conduct various experiments, carry out vital assays, and develop innovative solutions in gene therapy, cell culture, and various other scientific endeavors. The growing demand for polybrene in laboratories to enhance viral transduction efficiency and genetic material delivery into cells has significantly driven the market’s growth. Researchers and scientists in laboratories across the globe rely on polybrene to perform their experiments, ensuring accurate results of gene therapy, cell culture, and molecular biology projects. The ongoing advancements in biotechnology, pharmaceuticals, and genetic engineering augmenting the market’s demand over the forecast period.

Based on the regions, the global polybrene market has been segmented across North America, Europe, Asia-Pacific, South America and the Middle East & Africa. North America is expected to dominate the market share of around 45% in 2023, owing to the robust presence of the biotechnology and pharmaceutical industries in the region. With numerous research institutions, academic centers, and biotech companies engaged in cutting-edge genetic research and therapy development in the region, the polybrene market is expected to witness a positive outlook in the market. Also, the region's growing focus on regenerative medicine and personalized healthcare has accelerated the gene transfer technologies demand, further boosting the polybrene market’s growth. The increased investments in healthcare research and development, as well as rising funding for academic research, create a lucrative growth opportunity for the market.

Polybrene Market Key Players, 2023

The presence of established manufacturers and suppliers of polybrene holds a positive competitive landscape. These companies have a strong foothold in the market, owing to their years of experience, extensive distribution networks, and established customer relationships. They offer a wide range of product variants and have the capacity to meet the growing demand of both large-scale research institutions and smaller laboratories. The Major key players in the global polybrene market are:

• Tocris Bioscience (R&D Systems) 
• Merck 
• Applied Biological Materials 
• Biosharp
• APEXBIO
• Selleck Chemicals
• BP Biosciences
• Cellecta
• Glpbio
• MedChemExpress
• NACALAI TESQUE
• Genomeditech
• Solarbio
• Yeasen Biotechnology

Recent Developments

• In August 2023, Astellas Pharma’s wholly-owned subsidiary of Astellas US Holding, Inc. acquired Iveric bio, Inc. to enhance its ophthalmology expertise and capabilities of Iveric Bio and its global reach.
• In April 2022, Merck acquired the MAST (Modular Automated Sampling Technology) platform from Lonza. It is an automated, aseptic bioreactor sampling system that helps in analyzing and managing real-time data, including product attributes, in hours. The acquisition accelerates innovation in Merck’s Process Solutions business unit and expands its bioprocessing portfolio.  

Report Scope of the Global Polybrene Market

This market research study categorizes the polybrene market-based on type, and application area at the regional and global levels.

By Type Outlook (Sales, USD Million, 2019-2033)

• 1 Below
• 1-5
• 5 Above

By Application Outlook (Sales, USD Million, 2019-2033)

• Graduate School
• Laboratory
• Others

By Region Outlook (Sales, USD Million, 2019-2033)

• North America
  • US
  • Canada
  • Mexico
• Europe
  • Germany
  • Italy
  • France
  • UK
  • Spain
  • Poland
  • Russia
  • The Netherlands
  • Norway
  • Czech Republic
  • Rest of Europe
• Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Indonesia
  • Malaysia
  • Thailand
  • Singapore
  • Australia & New Zealand
  • Rest of Asia Pacific
• South America
  • Brazil
  • Argentina
  • Colombia
  • Rest of South America
• The Middle East & Africa
  • Saudi Arabia
  • UAE
  • South Africa
  • Northern Africa
  • Rest of MEA