According to the Market Statsville Group (MSG), the Global nutraceutical oral thin films Market was valued at USD 1800 million in 2023 and is expected to grow from USD 1962 million in 2024 to USD 5500 million by 2033, by exhibiting a CAGR of 9% during the forecast period (2024-2033)
The nutraceutical oral thin films are thus proving to be a fast-growing sub-sector in the dietary supplements market. These excellent innovative products create a new approach to delivering the nutraceutical ingredients in the form of micronized, thin, and flexible film that dissolves in the mouth and is a faster and more efficient form of dosage forms as compared to pills, capsules, and powders. Some of the factors that have compounded growth in the market include the discreet and portable formulation of oral thin films that do not require water and can be swallowed anytime. Oral thin films can improve the digestibility of some nutrients, making their uptake faster and more efficient than the form of supplements. Rising consumer preference for innovative, user-friendly, and discreet supplement options is contributing to the expansion of the market. Oral thin films containing essential vitamins (e.g., Vitamin C, B vitamins) and minerals (e.g., calcium, magnesium) are popular for daily health maintenance and addressing specific deficiencies. Thin films featuring herbal extracts (e.g., ginseng, echinacea) are used for their potential health benefits and convenience of administration.
Moreover, thin films designed to provide quick energy boosts often contain caffeine, B vitamins, or other stimulants. Supplements with ingredients like melatonin or valerian root in thin film form are used to promote better sleep and relaxation. Oral thin films are pretty handy: they don't require water to be taken and can't be swallowed. They are perfect for running individuals on the go and individuals who have an aversion to taking pills. They are also flat, so they may be taken away without much fanfare. Since they dissolve right away in the mouth, nutrient absorption is faster than taking tablet or capsule varieties that have to go through the body. This production requires advanced technology and precision, which makes the manufacturing process more expensive as compared to traditional supplement forms. The stability of active ingredients in the thin film matrix can prove a challenge, so does achieving lasting efficacy of the product. These nutraceutical oral thin films are regulated and abide by particular strict standards or laws, which are relative to the region of entry into that market.
Nutraceutical oral thin films are very thin strips of film designed to contain the active nutraceutical ingredient. When such a film is exposed to saliva in the mouth, it will dissolve or disintegrate, and nutrients will then be directly absorbed into the bloodstream. The ease of use and rapid onset of action make nutraceutical oral thin films a sought product.
The main factor driving the popularity and growth that has been related to nutraceutical oral thin films has been the improvement in bioavailability. Bioavailability is defined as the level and rate at which active ingredients of a supplement are absorbed into the bloodstream and thus, ready to be utilized by the body. Oral thin films are increasingly known for their higher potency of bioavailability more than the conventional supplement forms that include tablets, capsules, and powders. Oral thin films facilitate the direct absorption of nutrients through the oral mucosa. Studies conducted by NIH showed that bioavailability is 30-50% higher for oral thin films compared to swallowing conventional tablets or capsules. The explanation is based on a faster dissolution process followed by absorption in the mouth, thereby bypassing the GI tract.
Furthermore, Oral thin films dissolve quickly in the mouth, so they can be absorbed directly through mucous membranes in the space under the tongue and the space of the cheek. This is beyond the digestive system, where such nutrients can degrade or otherwise not be very well absorbed. Direct absorption into the bloodstream is also quicker and more effective than a route to systemic circulation. Since oral thin films let nutrients come in direct contact with the blood, they are absorbed faster. Besides, the gel matrix of the oral thin films also protects susceptible nutrients from degradation. For instance, according to bioavailability studies, survival rates of probiotics in oral thin films are 25% higher than those in powders or capsules. This means that a larger part of the probiotics survive and remain active when they hit the intestines, reported NIH. Special and complex manufacturing processes for nutraceutical oral thin films involve advanced technology and high precision.
To affect the cost, the production complexity results in implications for the quality of the final product. A formulation of oral thin films involves the selection and blending of active ingredients with excipients and a film-forming agent. All the components should be compatible with each other to avoid interactions that may detrimentally affect the stability or effectiveness of the final product. Nutraceutical oral thin films are also highly expensive to produce compared to the traditional supplement forms that comprise tablets or capsules. According to NIH, the average manufacturing cost of oral thin films ranges from 20% and up to 40% more due to specialized equipment and advanced technology. It includes the costs of ingredient selection, film-forming processes, and quality control.
Additionally, To keep the degradation of nutraceutical ingredients by environmental factors, such as moisture and light, and, of course, heat, at bay, stability testing is performed to ensure that active ingredients are maintained for the entire shelf life of the product. Therefore, comprehensive testing in different conditions may confirm the performance of the film. The investment in good quality or accurate manufacturing equipment for oral thin films mostly consists of the cost range from $ 500,000 to $1 million in terms of devices such as coaters and cutters. It will standardize the final product. The matrix of the oral thin film consists of polymers and gelling agents usually hydroxypropyl methylcellulose (HPMC), gelatin, or pectin. The correct choice of material would be a determinant for the required dissolution rate and other mechanical properties of the film.
The study categorizes the nutraceutical oral thin films market based on ingredient, application, and distribution channel area at the regional and global levels.
Based on the application, the nutraceutical oral thin films market segment about the application may focus on supplements that will help in general health maintenance and wellness. This area comprises a wide range of products for nutrition support, bodily functions, and quality of life enhancement. Key growth drivers are rising health consciousness, a higher prevalence of chronic diseases, and a greater preference for the more convenient supplement forms with improved bioavailability. Consumers are highly seeking more convenient and consumer-friendly supplement forms. Oral thin films are one of the most hassle-free forms available which do not require water or swallowing.
However, one observes a new trend towards personalized health solutions. These oral thin films can be formulated to meet specific nutritional needs, such as tailored dosages or targeted nutrient delivery. Oral thin films containing essential vitamins, such as Vitamin C, Vitamin D, and B vitamins, are very popular because they help to sustain the function of the immune system, contribute to good bone health, and provide energy. NIH research has shown that orally delivered thin-film vitamins can be up to 50% more bioavailable than traditionally dosed tablets. The ones containing calcium, magnesium, and iron contribute to the well-being of bones, muscles, and general health. They have been designed with delivery efficiency in mind to maximize absorption with minimal gastrointestinal burden.
Based on the region, the North American region, particularly the United States, is strong in terms of nutraceutical oral thin films market share. This region is referred to as the 'land of innovation' in nutraceuticals. R&D in North America is targeted towards oral thin films by improving the efficacy and bioavailability of drugs. High awareness among consumers towards convenient, effective, and non-invasive supplement forms is contributing to the growth of oral thin films in North America. The major players in the market are Pfizer Inc., DSM Nutritional Products, and Amway Corporation. These companies are focusing on R&D to develop advanced oral thin-film technologies.
The nutraceutical oral thin films market is strong and a strong competitor in the industry. It is, therefore, capitalizing plays like partnerships, product launches, acquisitions, agreements, and growth to enhance its position in the market. Most company divisions focus on expanding their operations into all corners of the world and forging long-term partnerships.
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