Description

The global natural killer cells therapeutics market size is expected to grow from USD 2,708.9 million in 2021 to USD 10,113.5 million by 2030, at a CAGR of 15.1% from 2022 to 2030. Natural killer cells are effector lymphocytes of the innate immune system that control several types of tumors and microbial infections by limiting their spread and subsequent tissue damage. Natural killer cell therapy is cellular immunotherapy, just like CAR-T-cell therapy. Like T-cells, NK cells also form part of the immune system and attack germs and other malignant cells. Unlike T-cells, however, NK cells are not tailored to specific antigens.

Natural killer (NK) cells are large granular lymphocytes that respond quickly to a pathological challenge. Also, they are responsible for producing immunoregulatory cytokines. Furthermore, they act as an important component of the innate immune system of a human. The main role of NK cells is to generate an immune response against malignancies and viral infections.

The rise in the adoption of NK cells to treat infections, cancer, and liver diseases are the factor that is driving the global market of natural killer cells therapeutics. Moreover, NK cells play a pivotal role in tumor immune surveillance, which boosts the adoption of NK therapeutics across the globe. The rise in the awareness among the population regarding various immunotherapies and increase in R&D for the development of bi-specific antibodies for engaging NK cells to eliminate tumor cells propel the global market growth. But, the lack of specificity and poor in-vivo survival of the cells limit the growth of natural killer cell therapeutics. In addition, higher costs associated with the therapies and adverse side effects are expected to hamper the market growth in the coming years. On the contrary, a significant surge in R&D activities toward developing immunotherapy in the developing economies is projected to offer lucrative opportunities as per the NK cell therapeutics market forecast.

Scope of the Natural Killer Cells Therapeutics

The study categorizes the natural killer cells therapeutics market based on therapeutics, application, and end-users at the regional and global levels.

By Therapeutics Outlook (Sales, USD Million, 2017-2030)

• NK Cell Therapies
• NK Cell Directed Antibodies

By Application Outlook (Sales, USD Million, 2017-2030)

• Gastrointestinal Diseases
• Cancer
• Immunoproliferative Disorders
• Others

By End-Users Outlook (Sales, USD Million, 2017-2030)

• Research Centers & Institutes
• Hospitals
• Others

By Region Outlook (Sales, USD Million, 2017-2030)

• North America (US, Canada, Mexico)
• South America (Brazil, Argentina, Colombia, Peru, Rest of Latin America)
• Europe (Germany, Italy, France, UK, Spain, Poland, Russia, Slovenia, Slovakia, Hungary, Czech Republic, Belgium, the Netherlands, Norway, Sweden, Denmark, Rest of Europe)
• Asia Pacific (China, Japan, India, South Korea, Indonesia, Malaysia, Thailand, Vietnam, Myanmar, Cambodia, the Philippines, Singapore, Australia & New Zealand, Rest of Asia Pacific)
• The Middle East & Africa (Saudi Arabia, UAE, South Africa, Northern Africa, Rest of MEA)

Natural killer cells therapeutics market, by end-users

The natural killer cells therapeutics market is divided into research centers & institutes, hospitals, and others based on end-users. Various ongoing R&D activities such as NK cells & immunological memory improvements, cell-based therapies, and stress-induced self-recognition are currently in progress. Moreover, certain immuno-monitoring studies are being performed to determine NK cells' usage. In hospitals, NK cell therapies are used to treat cancers using genetic engineering. Also, these cells are used as a therapeutic tool to cure immunoproliferative disorders, various cancers, gastrointestinal diseases, and infectious diseases due to their ability to detect transformed cells.

Furthermore, several medical clinical trials are performed to evaluate the safety and the anti-tumor effects of NK cells. The study's primary objective is to determine the safety of NK cells’ doses against cancers and malignancies. Moreover, NK cell therapeutics involves clinical and experimental research to provide cost-effective treatments with improved success rates. Presently, research is being carried out for the adoptive transfer of haploidentical NK cells for the consolidated therapy of pediatric acute myeloid leukemia. Therefore, NK cell therapeutics have promising applications in various research institutes.

Asia Pacific accounts for the highest CAGR during the forecast period

North America accounted for the highest share in 2021 in the global market of natural killer cells therapeutics. This is attributed to a significant increase in the prevalence of cancer in this region. During the forecast period,  the Asia-Pacific market is anticipated to grow at the fastest pace, owing to an increase in cancer patients, improvement in healthcare facilities, and a surge in the geriatric population.

Though, the complexity in regulatory frameworks regarding the approval of immunotherapy is expected to hamper the market's growth during the forecast period. Conversely, a high incidence of cancer is anticipated to boost the growth of the cancer immunotherapy market, which will fuel the growth of the NK cells therapeutics market.

Key Market Players

The natural killer cells therapeutics market is mildly concentrated in nature with few numbers global players operating in the market such as Affimed N.V., Fate Therapeutics, Fortress Biotech, Celgene Corporation, Glycostem Therapeutics BV, Nantkwest Inc., Nkarta Therapeutics, Inc., NKT Therapeutics Inc., Innate Pharma S.A., and Ziopharm Oncology Inc.

Key Issues Addressed

• What is the market size by various segmentation of the natural killer cells therapeutics by region and its respective countries?
• What are the customer buying behavior, key takeaways, and Porter's five forces of the natural killer cells therapeutics market?
• What are the key opportunities and trends for manufacturers involved in the natural killer cells therapeutics supply chain?
• What are the market's fundamental dynamics (drivers, restraints, opportunities, and challenges)?
• What and how are regulations, schemes, patents, and policies impacting the market's growth?
• What are the upcoming technological solutions influencing market trends? How will existing companies adapt to the new change in technology?
• The market player positioning, top winning strategies by years, company product developments, and launches will be?
• How has COVID-19 impacted the global market's demand and sales of natural killer cell therapeutics? Also, the expected BPS drop or rise count of the market and market predicted recovery period.
• Detailed analysis of the competitors and their latest launch, and what are the prominent startups introduced in the target market? Also, detailed company profiling of 25+ leading and prominent companies in the market.